In 2010, LEGO released 6 Harry Potter sets across 2 subthemes, all of these sets have been retired. Subthemes for that year included Chamber of Secrets and HalfBlood Prince. For that year, the total price of all retail sets cost $341, today those sets are valued around $845, a growth of 148%.
Most valuable 2010 LEGO Harry Potter set
4842 Hogwarts Castle $241.60
Highest growth 2010 Harry Potter set
4736 Freeing Dobby +266.70%
6 sets

4736 Freeing Dobby

Theme / Subtheme Harry Potter / Chamber of Secrets
Year 2010
Pieces / Minifigs 73 / 3
Availability Retired
4736 LEGO Harry Potter Chamber of Secrets Freeing Dobby
Retail $10.99
Value $40.30
Growth  +266.7%
Annual growth 6.7%

4737 Quidditch Match

Theme Harry Potter
Year 2010
Pieces / Minifigs 153 / 5
Availability Retired
4737 LEGO Harry Potter Quidditch Match
Retail $19.99
Value $68.86
Growth  +244.5%
Annual growth 5.4%

4738 Hagrid's Hut

Theme Harry Potter
Year 2010
Pieces / Minifigs 442 / 4
Availability Retired
4738 LEGO Harry Potter Hagrid's Hut
Retail $39.99
Value $93.28
Growth  +133.3%
Annual growth 6.1%

4840 The Burrow

Theme / Subtheme Harry Potter / Half-Blood Prince
Year 2010
Pieces / Minifigs 568 / 6
Availability Retired
4840 LEGO Harry Potter Half-Blood Prince The Burrow
Retail $59.99
Value $195.59
Growth  +226.0%
Annual growth 8.4%

4841 Hogwarts Express

Theme Harry Potter
Year 2010
Pieces / Minifigs 646 / 5
Availability Retired
4841 LEGO Harry Potter Hogwarts Express
Retail $79.99
Value $205.70
Growth  +157.2%
Annual growth 6.2%

4842 Hogwarts Castle

Theme Harry Potter
Year 2010
Pieces / Minifigs 1,290 / 11
Availability Retired
4842 LEGO Harry Potter Hogwarts Castle
Retail $129.99
Value $241.60
Growth  +85.9%
Annual growth 5.5%